EXOGENOUS APPLICATION OF RNAI-INDUCING DOUBLE-STRANDED RNA INHIBITS APHID-MEDIATED TRANSMISSION OF A PLANT VIRUS

Exogenous Application of RNAi-Inducing Double-Stranded RNA Inhibits Aphid-Mediated Transmission of a Plant Virus

Plant viruses are difficult to control, and they decrease both the quality and yield of crops, thus threatening global food security.A new approach that uses topical application of double-stranded RNA (dsRNA) to induce antiviral RNA-interference has been shown to be effective at preventing virus infection in a range of plants following mechanical i

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Assessing pH-Dependent Conformational Changes in the Fusion Peptide Proximal Region of the SARS-CoV-2 Spike Glycoprotein

One of the entry mechanisms of the SARS-CoV-2 coronavirus into host cells involves endosomal acidification.It has been proposed that under acidic conditions, the fusion peptide proximal region (FPPR) of the SARS-CoV-2 spike glycoprotein acts as a pH-dependent switch, modulating immune response accessibility by influencing the positioning of the rec

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